Capital Reallocation
Recoverable Waste Becomes a New Funding Source
By 2031, Protocol‑Plus transforms recoverable waste from lost capital into a reinvestable pool. Over a decade, this compounds into capital that can fund entirely new therapeutic programs.
Annual Savings by 2031
~$8–10B
Recoverable waste per year
5-Year Cumulative
~$45B
2026–2031
10-Year Cumulative
~$108B
2026–2036
NIH Annual Budget
~$47B
Reference scale (FY2026)
Cumulative & Annual Savings Over Time
Annual savings (ramps to ~$8–10B by 2031)
Cumulative savings (reaches ~$108B by 2036)
Context:
The cumulative $108B over 10 years is equivalent to approximately 2.3 years of NIH’s annual translational research budget. This capital can be recycled into entirely new therapeutic programs rather than lost to failed trials and false signals.
The Reinvestment Opportunity
By 2031, higher reproducibility unlocks ≈$8–10B/year of recoverable waste that would otherwise be lost to false-positive trials and dead-end programs. Over a decade, this compounds into ≈$108B—capital that can be recycled into new programs rather than dissipated through inefficiency.
Waste is simply capital waiting to be redirected toward discovery.